Joined in 2023 
82 
63 About this deal
Measuring the efficacy of therapies for acute URTIs and bronchitis is challenging as symptoms typically recede after 5–11 days, regardless of intervention [ 27]. Correspondingly, the clinical condition of participants improved in both treatment and comparison groups. Values for the minimal clinically important difference (MID), or the smallest change perceived by patients as important, are available for two of the tools used to measure cough severity in the studies in our review: 17 mm for the Visual Analog Scale (VAS) and 2 points for the Leicester Cough Questionnaire (LCQ, Online Resource 2) [ 28]. One RCT reported VAS differences of 11.1 and 17.9 mm between treatment and placebo groups at day 3 and at the end of the treatment period, respectively [ 23]. Based on the MID, the effect of ivy leaf treatment at 3 days was likely too small to be perceived as important by patients but the difference after 7 days was potentially clinically noticeable. The CCT reported an LCQ difference of 4.3 at the end of the treatment period, indicating a potentially clinically noticeable difference [ 26]. Hay IC, Jamieson M, Ormerod AD. Randomized trial of aromatherapy. Successful treatment for alopecia areata. Arch Dermatol 1998;134:1349-52. View abstract.
Klarić M, et al. (2007). Antifungal activity of thyme ( Thymus vulgaris L.) essential oil and thymol against moulds from damp dwellings.This section needs additional citations for verification. Please help improve this article by adding citations to reliable sourcesin this section. Unsourced material may be challenged and removed. ( September 2012) ( Learn how and when to remove this template message) Thyme might act like estrogen in the body. Taking thyme along with estrogen might decrease the effects of estrogen. Store the product out of reach of children at room temperature. It is recommended to protect against the effects of moisture and light. Ali, Z., Daniyal, M., Adhia, M. K., Alam, A., Sarfaraz, B., Sattar, A., et al. (2017, March). To evaluate the efficacy and safety of CofNovex plus (EMA) syrup. Pakistan Journal of Pharmaceutical Sciences, 30(2(Suppl.)), 591–596. Wagner, U. (2009). Phytotherapy research. A thyme-ivy combination using synergy effects in action and research. Pharmazie in Unserer Zeit, 38(1), 83–85.
Buechi, S., Vogelin, R., von Eiff, M. M., Ramos, M., and Melzer, J. Open trial to assess aspects of safety and efficacy of a combined herbal cough syrup with ivy and thyme. Forsch.Komplementarmed.Klass.Naturheilkd. 2005;12(6):328-332. View abstract. Alshaikh NA, et al. (2021). Susceptibility of fluconazole-resistant Candida albicansto thyme essential oil.Abdel-Rahim IR, et al. (2017). Using of endophytic Saccharomycopsis fibuligera and thyme oil for management of gray mold rot of guava fruits. In my blog ‘What type of cough do you have?’ I discuss the various types of cough that exist, however, for now here a few of the most common examples. Thyme is indigenous to the Mediterranean region. [1] Wild thyme grows in the Levant, where it might have been first cultivated. Ancient Egyptians used thyme for embalming. [2] The ancient Greeks used it in their baths and burnt it as incense in their temples, believing it was a source of courage. The spread of thyme throughout Europe was thought to be due to the Romans, as they used it to purify their rooms and to "give an aromatic flavour to cheese and liqueurs". [3] In the European Middle Ages, the herb was placed beneath pillows to aid sleep and ward off nightmares. [4] In this period, women also often gave knights and warriors gifts that included thyme leaves, as it was believed to bring courage to the bearer. Thyme was also used as incense and placed on coffins during funerals, as it was supposed to assure passage into the next life. [5]
Agbor GA, Oben JE, Ngogang JY, et al. Antioxidant capacity of some herbs/spices from cameroon: a comparative study of two methods. J Agric Food Chem 2005;53:6819-24. . View abstract. Grande S, Bogani P, de Saizieu A, et al. Vasomodulating potential of mediterranean wild plant extracts. J Agric Food Chem 2004;52:5021-6. . View abstract. Aydin S, Basaran AA, Basaran N. Modulating effects of thyme and its major ingredients on oxidative DNA damage in human lymphocytes. J Agric Food Chem 2005;53:1299-305. . View abstract.The human lung carcinoma cell line A549 obtained from DSMZ was cultivated in RPMI 1640 medium supplemented with 2 mM L-glutamine, 100 U/mL penicillin, 100 μg/mL streptomycin, and 10 % fetal calf serum (all Gibco by Life Technologies, Darmstadt, Germany). For FCS experiments cells were seeded in a density of 1.7–3.4 × 10 4 cells/cm 2 on heat-sterilized glass coverslips (#1, ∅18 mm, VWR International GmbH, Langenfeld, Germany) and maintained in 12x multi-well chambers (Nunc, Langenselbold, Germany) at 37 °C and 5% CO 2. Cells were used for FCS experiments after three to four days in culture at 80–90 % confluency. Ebrahimi, H., Fallahi, M., Khamaneh, A. M., Ebrahimi Saadatlou, M. A., Saadat, S., & Keyhanmanesh, R. (2016, March). Effect of α-Hederin on IL-2 and IL-17 mRNA and miRNA-133a levels in lungs of ovalbumin-sensitized male rats. Drug Development Research, 77(2), 87–93. Sakkas H, Papadopoulou C. Antimicrobial activity of Basil, Oregano and Thyme essential oils. J Microbiol Biotechnol. 2016 Dec 20. doi: 10.4014/jmb.1608.08024. [Epub ahead of print] Review. View abstract. Lang, C., Röttger-Lüer, P., & Staiger, C. (2015, August). A valuable option for the treatment of respiratory diseases: Review on the clinical evidence of the ivy leaves dry extract EA 575®. Planta Medica, 81(12–13), 968–974.
Great Deal 
New Comment